Causes of endometrial displacement

Endometrial displacement may be caused by genetics, immune factors, hormonal abnormalities, surgical injury, uterine cavity infection and other reasons.

1. Genetic factors

Some patients with endometrial translocation have familial aggregation and specific genetic susceptibility. Such patients can undergo genetic testing under the guidance of professional doctors. After diagnosis, hormone drugs can be used to delay the progression of the disease. Commonly used drugs include dydrogesterone tablets, norethindrone tablets, medroxyprogesterone acetate tablets, etc. Pollutants in the living environment such as dioxins may aggravate the disease in people with genetic predispositions.

2. Immune factors

Immune dysfunction can lead to abnormal recognition of intimal cells and increase the probability of ectopic implantation. Clinical manifestations include elevated CA125 levels, accompanied by symptoms such as infertility and worsening dysmenorrhea. Treatments to regulate immune function include immunomodulators such as cyclophosphate meglumine and transfer factor oral solution, which may be combined with laparoscopic surgery to remove lesions when necessary.

3. Hormone abnormalities

Excessive estrogen levels promote intimal cell proliferation and migration. Such patients are often accompanied by increased menstrual flow and irregular cycles, and ultrasound shows ovarian chocolate cysts. Treatment requires suppressing estrogen secretion. Commonly used drugs include GnRH analogues such as leuprolide microspheres for injection and goserelin sustained-release implants, combined with Chinese patent medicines such as Sanjie Analgesic Capsules.

4. Surgical injuries

Uterine operations such as cesarean section and induced abortion may bring endometrial cells to the pelvic cavity. If progressive dysmenorrhea and dyspareunia occur after surgery, you need to be vigilant about displacement. Thickening of the sacral ligament can be found through vaginal ultrasound. Prophylactic use of short-acting contraceptives such as drospirenone and ethinylestradiol tablets can reduce the risk of recurrence. Severe adhesions require combined hystero-laparoscopic surgery.

5. Uterine cavity infection

Tissue adhesions and abnormal contractions caused by chronic endometritis can lead to reflux of menstrual blood. Most patients have lower abdominal pain and abnormal secretions, and etiological examination shows mycoplasma or chlamydial infection. Treatment requires doxycycline hydrochloride dispersible tablets combined with Fuke Qianjin capsules, and severe cases require uterine infusion treatment.

It is necessary to avoid strenuous exercise and sexual life during menstruation and reduce the number of uterine cavity operations. Ensure 30 minutes of aerobic exercise every day, such as brisk walking and swimming, and supplement with appropriate amounts of vitamin E and deep-sea fish oil. When dysmenorrhea is obvious, apply heat to the lower abdomen, choose pure cotton underwear with good breathability and change it every day. It is recommended to have a gynecological ultrasound examination every year. If you have abnormal menstruation or persistent abdominal pain, you should see a doctor promptly.