What causes endometrial thickening?
Asked by:Gloria
Asked on:Apr 12, 2026 03:28 PM
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Giuliana
Apr 12, 2026
Endometrial thickening may be caused by endocrine disorders, endometrial polyps, endometrial hyperplasia, endometritis, endometrial cancer, etc. Endometrial thickening usually presents with symptoms such as abnormal menstruation, non-menstrual bleeding, and lower abdominal pain, and can be intervened through hormone therapy, surgical resection, etc.
1. Endocrine disorders
Long-term mental stress or abnormal ovarian function may lead to excessive estrogen levels and stimulate excessive endometrial proliferation. This type of situation is often accompanied by irregular menstrual cycles and increased menstrual flow. It is recommended to improve by adjusting work and rest, reducing stress, etc. If necessary, follow the doctor's advice and use progesterone capsules, dydrogesterone tablets and other drugs to adjust hormone levels.
2. Endometrial polyps
Local overgrowth of the endometrium to form polypoid protrusions may be related to chronic inflammation or hormonal stimulation. Common symptoms are prolonged menstruation and irregular bleeding. The diagnosis requires hysteroscopy. Smaller polyps can be observed and followed up, while larger polyps require hysteroscopic polyp resection.
3. Endometrial hyperplasia
The ratio of endometrial glands to stroma is abnormally increased and is divided into simple hyperplasia and complex hyperplasia. Patients may experience post-amenorrhea bleeding or heavy periods. Treatment requires the selection of progesterone drugs such as medroxyprogesterone acetate tablets or levonorgestrel intrauterine sustained-release system according to the pathological type.
4. Endometritis
An inflammatory response in the endometrium triggered by bacterial infection may lead to tissue edema and thickening. Typical symptoms include sinking pain in the lower abdomen, abnormal discharge and fever. In the acute stage, ceftriaxone sodium for injection combined with metronidazole sodium chloride injection is needed to fight infection. Chronic inflammation can be treated with traditional Chinese medicine enema.
5. Endometrial cancer
Endometrial malignant lesions may manifest as abnormal thickening in the early stages, and high-risk factors include obesity, diabetes, and long-term estrogen exposure. Common symptoms are postmenopausal bleeding or bloody discharge. Diagnostic dilation and curettage is required to confirm the diagnosis, and extrafascial total hysterectomy or radiotherapy and chemotherapy are selected according to the staging.
You should pay attention to keeping your vulva clean every day and avoid frequent use of estrogen-containing health products. Women over 35 years old are recommended to undergo gynecological ultrasound examinations every year. If abnormal bleeding occurs, they should seek medical treatment promptly. Increasing the intake of cruciferous vegetables in the diet, limiting high-fat foods, and moderate exercise can help maintain hormone balance. All drug treatments must be carried out under the guidance of a doctor, and self-administration of hormonal drugs is prohibited.
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